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Global accumulation of circRNAs during aging in Caenorhabditis elegans
Circular RNAs (CircRNAs) are a newly appreciated class of RNAs that lack free 5' and 3' ends, are expressed by the thousands in diverse forms of life, and are mostly of enigmatic function. Ostensibly due to their resistance ...
Transcriptome profiling of aging Drosophila photoreceptors reveals gene expression trends that correlate with visual senescence
Aging is associated with functional decline of neurons and increased incidence of both neurodegenerative and ocular disease. Photoreceptor neurons in Drosophila melanogaster provide a powerful model for studying the molecular ...