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    CircRNA accumulation in the aging mouse brain 

    Gruner, Hannah N.; Cortes-Lopez, Mariela; Cooper, Daphne A.; Bauer, Matthew; Miura, Pedro (2016)
    Circular RNAs (circRNAs) are a newly appreciated class of RNAs expressed across diverse phyla. These enigmatic transcripts are most commonly generated by back-splicing events from exons of protein-coding genes. This results ...
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    Global accumulation of circRNAs during aging in Caenorhabditis elegans 

    Cortes-Lopez, Mariela; Gruner, Matthew R.; Cooper, Daphne A.; Gruner, Hannah N.; Voda, Alexandru-Ioan; van der Linden, Alexander M.; Miura, Pedro (2018)
    Circular RNAs (CircRNAs) are a newly appreciated class of RNAs that lack free 5' and 3' ends, are expressed by the thousands in diverse forms of life, and are mostly of enigmatic function. Ostensibly due to their resistance ...
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    Loss of adult skeletal muscle stem cells drives age-related neuromuscular junction degeneration 

    Liu, Wenxuan; Klose, Alanna; Forman, Sophie; Paris, Nicole D.; Pierre, Lan Wei-La; Cortes-Lopez, Mariela; Tan, Aidi; Flaherty, Morgan; Miura, Pedro; Dirksen, Robert T.; Chakkalakal, Joe V. (2017)
    Neuromuscular junction degeneration is a prominent aspect of sarcopenia, the age associated loss of skeletal muscle integrity. Previously, we showed that muscle stem cells activate and contribute to mouse neuromuscular ...