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Hashimoto’s thyroiditis (HT), named after its discoverer Hakaru Hashimoto, is a chronic
autoimmune inflammatory disease. HT develops when an autoimmune response causes
inflammation of the thyroid gland that ultimately leads to the destruction of thyroid tissue,
effectively killing the organ. An affected patient may simply be asymptomatic during the initial
phases or he or she can present with many vague underlying symptoms due to the broad range of
thyroid hormones functions, including mood and appetite regulation (Tomer and Huber
233). However, serious complications such as myxedema coma, Hashimoto’s encephalopathy,
and even thyroid cancer can occur. While a very effective hormone replacement therapy exists,
there is still no cure that can reverse or halt the damage caused by Hashimoto’s thyroiditis. The
research for this thesis will be gathered from academic papers and medical literature
documenting the condition.
This thesis was written to condense and organize the medical and research community's
collective knowledge of Hashimoto’s thyroiditis. Also included, is the outline of a case study
based loosely on a real patient treated while I was shadowing an internist in Elko, Nevada. The
case study includes lab findings and treatment details. Discussed in the thesis will be in-depth
information regarding the pathology of HT and the treatment options for the present and near
future. Overall, this thesis is meant to cover everything a practicing physician would need to
know to effectively treat HT and it also delves into the cutting edge research being conducted by
Clinical Analysis and Review of Literature Associated with Hashimoto's Thyroiditis