Bio-fortification of Rice by Constructing a Starch-Binding and Lysine-Rich Protein to Supplement Diets of Lysine Deficient Populations
Biochemistry and Molecular Biology
Biochem and Molecular Biology
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Lysine is an essential amino acid in the human diet and when consumed at insufficient levels, can lead to osteoporosis, reproductive disorders, and heart diseases. In an approach to increase the nutritional content of lysine in rice, a modular protein composed of a starch-binding protein, CBM 21,was fused to a lysine-rich protein, ABY716351. This alternative approach was geared towards genetically engineering a lysine-rich protein that can be added to white rice after milling. This approach is much different than the more classic molecular approach of genetically modifying the rice itself. This was done in order to gain a more acceptable perception of genetic engineering approach to fortifying rice with lysine for lysine deficient populations worldwide.