| Description | Pernicious anemia is a type of anemia falling in the category of megaloblastic
anemias – a group of anemias in which red blood cells are larger than normal. This type
of anemia is characterized by a deficiency in Vitamin B12 – a vitamin necessary for the
production of red blood cells. With successful treatment, pernicious anemia can be
successfully managed allowing those who suffer from it to live with their diagnosis.
However, if treatment is not sought, subsequent sequelae may ensue in the form of
disease. Such sequelae include gastric cancer, neurological disorders, achlorhydria, and
concomitant iron deficiency anemia. This paper will discuss the biological mechanisms
and complications associated with pernicious anemia; specifically, the complications
which have somewhat unclear mechanisms of occurrence. This information will be used
to gain a further understanding of pernicious anemia. | |
University of Nevada, Reno
