Browsing Community Health Sciences - Faculty Research by Author "Li, Yapei"

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Construction and verification of CYP3A5 gene polymorphisms using a Saccharomyces cerevisiae expression system to predict drug metabolism

Lu, Yao; Zhong, Hua; Tang, Qing; Huang, Zhijun; Jing, Ningning; Smith, Julie; Miao, Rujia; Li, Yapei; Yuan, Hong (2017)

The present study evaluated the ability of a Saccharomyces cerevisiae expression system to predict the pharmacokinetic (PK) activity of a calcium channel blocker in patients with distinct cytochrome P450 3A5 (CYP3A5) ...