University of Nevada, Reno
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Terthiophene Compounds as Photosensitizing Agents in Photodynamic Therapy
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Date
2013Type
ThesisDepartment
Chemistry
Degree Level
Honors Thesis
Degree Name
Chemistry
Abstract
Terthiophene compounds are naturally occurring in marigolds and can be used as
photosensitizing agents in photodynamic therapy. As of now, photodynamic therapy is
limited by its use of light that can only penetrate shallow tissues. Synthesis of
pyridineterthiophene-based compounds has been studied due to its increased conjugation
leading to longer wavelengths. Using low frequency infrared light , up to five inches of
tissue can be penetrated. This would be a breakthrough to the field of photochemistry and
make photodynamic therapy more widely available for use. This report summarizes the
synthesis of pyridinethiophene-based compounds with fluorescence potential application
in photodynamic therapy.
Permanent link
http://hdl.handle.net/11714/371Additional Information
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