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Guillain-Barre Syndrome: Identification of Acute Motor Axonal Neuropathy and Representative Case Study
AdvisorBaker, Jonathan E.
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Guillain–Barré Syndrome is an autoimmune disease that leaves up to 20 percent of patients severely disabled and approximately five percent dead(Yuki,2012). This is often due to a misdiagnoses which stems from a lack of knowledge about the variants of GBS and their pathology. Molecular mimicry is one possible pathogenic mechanism of auto-immune diseases such as Guillain–Barré(Blank, 2007). Acute Motor Axonal Neuropathy GBS is often linked to C.jejuni infections. This is attributed Anti-GM1 IgG Antibodies Affect on the Nodes of Ranvier which is clearly outlined in a stepwise manner starting from infection and ending with treatment. This is a possible explanation of the link between C.jejuni and AMAN GBS. A case study of a 46 year old patient presenting with GBS-like symptoms is used to demonstrate how to correctly diagnosis AMAN GBS.