If you have any problems related to the accessibility of any content (or if you want to request that a specific publication be accessible), please contact us at firstname.lastname@example.org.
Suitability of Bupropion SR for nicotine-dependent smokers: Problems in a practice setting
AuthorKohlenberg, Barbara S.
Antonuccio, David O.
Hayes, Steven C.
Gifford, Elizabeth V.
Piasecki, Melissa P.
AltmetricsView Usage Statistics
The full text of the article is available at:
Background: Bupropion SR ( Zyban) has been shown in randomized controlled trials to be an efficacious pharmacological aid for smoking cessation; however, recent reports have raised serious concerns about the breadth of its applicability without complications or contraindications. Methods: We examined this issue in a well-documented medical population, i.e. veterans volunteering to participate in a smoking cessation treatment research program involving the use of bupropion SR. Results: Overall, 22% of the 78 subjects who met the study criteria were appropriate for and completed the course of medication. Conclusions: Thus, bupropion SR in nicotine-dependent veterans may not be broadly applicable when conservative prescribing guidelines are carefully followed. Copyright (C) 2004 S. Karger AG, Basel.