Now showing items 45-64 of 111

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    Gene expression of the liver in response to chronic hypoxia. 

    Baze, Monica M.; Schlauch, Karen A.; Hayes, Jack P. (5/1/2010)
    Hypoxia is an important ecological, evolutionary, and biomedicalstressor. While physiological acclimatization of mammals to hypoxia is wellstudied, the variation in gene expression that underlies acclimatization is not ...
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    Genome-wide association analysis identifies genetic variations in subjects with myalgic encephalomyelitis/chronic fatigue syndrome 

    Schlauch, K. A.; Khaiboullina, Svetlana F.; De Meirleir, Kenny L.; Rawat, S.; Petereit, J.; Rizvanov, A. A.; Blatt, N.; Mijatovic, Tatjana; Kulick, Doina; Palotas, A.; Lombardi, Vincent C. (2016)
    Myalgic encephalomyelitis, also known as chronic fatigue syndrome or ME/CFS, is a multifactorial and debilitating disease that has an impact on over 4 million people in the United States alone. The pathogenesis of ME/CFS ...
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    Genomic insights into the Ixodes scapularis tick vector of Lyme disease 

    Gulia-Nuss, Monika; Nuss, Andrew B.; Meyer, Jason M.; Sonenshine, Daniel E.; Roe, R. Michael; Waterhouse, Robert M.; Sattelle, David B.; de la Fuente, Jose; Ribeiro, Jose M.; Megy, Karine; Thimmapuram, Jyothi; Miller, Jason R.; Walenz, Brian P.; Koren, Sergey; Hostetler, Jessica B.; Thiagarajan, Mathangi; Joardar, Vinita S.; Hannick, Linda I.; Bidwell, Shelby; Hammond, Martin P.; Young, Sarah; Zeng, Qiandong; Abrudan, Jenica L.; Almeida, Francisca C.; Ayllon, Nieves; Bhide, Ketaki; Bissinger, Brooke W.; Bonzon-Kulichenko, Elena; Buckingham, Steven D.; Caffrey, Daniel R.; Caimano, Melissa J.; Croset, Vincent; Driscoll, Timothy; Gilbert, Don; Gillespie, Joseph J.; Giraldo-Calderon, Gloria I.; Grabowski, Jeffrey M.; Jiang, David; Khalil, Sayed M. S.; Kim, Donghun; Kocan, Katherine M.; Koci, Juraj; Kuhn, Richard J.; Kurtti, Timothy J.; Lees, Kristin; Lang, Emma G.; Kennedy, Ryan C.; Kwon, Hyeogsun; Perera, Rushika; Qi, Yumin; Radolf, Justin D.; Sakamoto, Joyce M.; Sanchez-Gracia, Alejandro; Severo, Maiara S.; Silverman, Neal; Simo, Ladislav; Tojo, Marta; Tornador, Cristian; Van Zee, Janice P.; Vazquez, Jesus; Vieira, Filipe G.; Villar, Margarita; Wespiser, Adam R.; Yang, Yunlong; Zhu, Jiwei; Arensburger, Peter; Pietrantonio, Patricia V.; Barker, Stephen C.; Shao, Renfu; Zdobnov, Evgeny M.; Hauser, Frank; Grimmelikhuijzen, Cornelis J. P.; Park, Yoonseong; Rozas, Julio; Benton, Richard; Pedra, Joao H. F.; Nelson, David R.; Unger, Maria F.; Tubio, Jose M. C.; Tu, Zhijian; Robertson, Hugh M.; Shumway, Martin; Sutton, Granger; Wortman, Jennifer R.; Lawson, Daniel; Wikel, Stephen K.; Nene, Vishvanath M.; Fraser, Claire M.; Collins, Frank H.; Birren, Bruce; Nelson, Karen E.; Caler, Elisabet; Hill, Catherine A. (2016)
    Ticks transmit more pathogens to humans and animals than any other arthropod. We describe the 2.1 Gbp nuclear genome of the tick, Ixodes scapularis (Say), which vectors pathogens that cause Lyme disease, human granulocytic ...
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    Glut4 Is Sorted from a Rab10 GTPase-independent Constitutive Recycling Pathway into a Highly Insulinresponsive Rab10 GTPase-dependent Sequestration Pathway after Adipocyte Differentiation 

    Brewer, Paul D.; Habtemichael, Estifanos N.; Romenskaia, Irina; Mastick, Cynthia C.; Coster, Adelle C. F. (2016)
    The RabGAP AS160/TBC1D4 controls exocytosis of the insulin-sensitive glucose transporter Glut4 in adipocytes. Glut4 is internalized and recycled through a highly regulated secretory pathway in these cells. Glut4 also cycles ...
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    Gut-associated plasmacytoid dendritic cells display an immature phenotype and upregulated granzyme B in subjects with HIV/AIDS 

    Boichuk, Sergei V.; Khaiboullina, Svetlana F.; Ramazanov, Bulat R.; Khasanova, Gulshat R.; Ivanovskaya, Karina A.; Nizamutdinov, Evgeny Z.; Sharafutdinov, Marat R.; Martynova, Ekaterina V.; DeMeirleir, Kenny L.; Hulstaert, Jan; Anokhin, Vladimir A.; Rizvanov, Albert A.; Lombardi, Vincent C. (2015)
    Plasmacytoid dendritic cells (pDCs) in the periphery of subjects with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) decrease over time, and the fate of these cells has been the subject of ...
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    GWAS and PheWAS of red blood cell components in a Northern Nevadan cohort 

    Read, Robert W.; Schlauch, Karen A.; Elhanan, Gai; Metcalf, William J.; Slonim, Anthony D.; Aweti, Ramsey; Borkowski, Robert; Grzymski, Joseph J. (PLoS ONE, 2019)
    In this study, we perform a full genome-wide association study (GWAS) to identify statistically significantly associated single nucleotide polymorphisms (SNPs) with three red blood cell (RBC) components and follow it with ...
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    Hantavirus Infection Suppresses Thrombospondin-1 Expression in Cultured Endothelial Cells in a Strain-Specific Manner 

    Khaiboullina, Svetlana F.; Morzunov, Sergey P.; St Jeor, Stephen C.; Rizvanov, Albert A.; Lombardi, Vincent C. (2016)
    Hantavirus infection is associated with two frequently fatal diseases in humans: Hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS). The pathogenesis of hantavirus infection is complex and ...
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    High quality draft genome sequences of Mycoplasma agassizii strains PS6(T) and 723 isolated from Gopherus tortoises with upper respiratory tract disease 

    Alvarez-Ponce, David; Weitzman, Chava L.; Tillett, Richard L.; Sandmeier, Franziska C.; Tracy, C. Richard (2018)
    Mycoplasma agassizii is one of the known causative agents of upper respiratory tract disease (URTD) in Mojave desert tortoises (Gopherus agassizii) and in gopher tortoises (Gopherus polyphemus). We sequenced the genomes ...
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    Humoral Immunity Profiling of Subjects with Myalgic Encephalomyelitis Using a Random Peptide Microarray Differentiates Cases from Controls with High Specificity and Sensitivity 

    Singh, Sahajpreet; Stafford, Phillip; Schlauch, Karen A.; Tillett, Richard R.; Gollery, Martin; Johnston, Stephen A.; Khaiboullina, Svetlana F.; De Meirleir, Kenny L.; Rawat, Shanti; Mijatovic, Tatjana; Subramanian, Krishnamurthy; Palotas, Andras; Lombardi, Vincent C. (2018)
    Myalgic encephalomyelitis (ME) is a complex, heterogeneous illness of unknown etiology. The search for biomarkers that can delineate cases from controls is one of the most active areas of ME research however, little progress ...
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    Identification of genes encoding enzymes catalyzing the early steps of carrot polyacetylene biosynthesis 

    Busta, Lucas; Yim, Won C.; LaBrant, Evan W.; Wang, Peng; Grimes, Lindsey; Malyszka, Kiah; Cushman, John C.; Santos, Patricia; Kosma, Dylan K.; Cahoon, Edgar B. (2018)
    Polyacetylenic lipids accumulate in various Apiaceae species after pathogen attack, suggesting that these compounds are naturally occurring pesticides and potentially valuable resources for crop improvement. These compounds ...
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    Identification of Ice Plant (Mesembryanthemum crystallinum L.) MicroRNAs Using RNA-Seq and Their Putative Roles in High Salinity Responses in Seedlings 

    Chiang, Chih-Pin; Yim, Won C.; Sun, Ying-Hsuan; Ohnishi, Miwa; Mimura, Tetsuro; Cushman, John C.; Yen, Hungchen E. (2016)
    The halophyte Mesembryanthemum crystal/loom (common or crystalline ice plant) is a useful model for studying molecular mechanisms of salt tolerance. The morphology, physiology, metabolism, and gene expression of ice plant ...
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    Identification of Phosphorylation Sites Altering Pollen Soluble Inorganic Pyrophosphatase Activity 

    Eaves, Deborah J.; Haque, Tamanna; Tudor, Richard L.; Barron, Yoshimi D.; Zampronio, Cleidiane G.; Cotton, Nicholas P. J.; de Graaf, Barend H. J.; White, Scott A.; Cooper, Helen J.; Franklin, Christopher H.; Harper, Jeffrey F.; Franklin-Tong, Vernonica E. (2017)
    Protein phosphorylation regulates numerous cellular processes. Identifying the substrates and protein kinases involved is vital to understand how these important posttranslational modifications modulate biological function ...
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    Identification of the MBF1 heat-response regulon of Arabidopsis thaliana. 

    Suzuki N; Sejima H; Tam R; Schlauch, Karen A; Mittler, Ron (6/1/2011)
    Brief periods of heat stress of even a few days can have a detrimental effect on yield production worldwide causing devastating economical and sociological impacts. Here we report on the identification of a new heat-response ...
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    Identification of tissue-specific, abiotic stress-responsive gene expression patterns in wine grape (Vitis vinifera L.) based on curation and mining of large-scale EST data sets. 

    Tillett, Richard L.; Ergul, A.; Albion, Rebecca L.; Schlauch, Karen A.; Cramer, Grant R.; Cushman, John C. (5/18/2011)
    Background: Abiotic stresses, such as water deficit and soil salinity, result in changes in physiology, nutrient use, and vegetative growth in vines, and ultimately, yield and flavor in berries of wine grape, Vitis vinifera ...
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    Inhibition of A beta(42) oligomerization in yeast by a PICALM ortholog and certain FDA approved drugs 

    Park, Sei-Kyoung; Ratia, Kiira; Ba, Mariam A.; Valencik, Maria; Liebman, Susan W. (2016)
    The formation of small A beta 42 oligomers has been implicated as a toxic species in Alzheimer disease (AD). In strong support of this hypothesis we found that overexpression of Yap1802, the yeast ortholog of the human AD ...
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    Inhibition of Aβ42 oligomerization in yeast by a PICALM ortholog and certain FDA approved drugs 

    Park, Sei-Kyoung; Ratia, Kiira; Ba, Mariam A.; Liebman; Maria Valencik; Liebman, Susan W. (1/20/2016)
    The formation of small Aβ42 oligomers has been implicated as a toxic species in Alzheimer disease (AD). In strong support of this hypothesis we found that overexpression of Yap1802, the yeast ortholog of the human AD risk ...
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    Insulin-Like Peptide Signaling in Mosquitoes: The Road Behind and the Road Ahead 

    Sharma, Arvind; Nuss, Andrew B.; Gulia-Nuss, Monika (2019)
    Insulin signaling is a conserved pathway in all metazoans. This pathway contributed toward primordial metazoans responding to a greater diversity of environmental signals by modulating nutritional storage, reproduction, ...
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    Inter-laboratory optimization of protein extraction method for the assessment of rice endogenous allergens 

    Satoh, Rie; Kitta, Kazumi; Labory-Carcenac, Bénédicte; Lang, Gang-Hua; Schegg, Kathleen; Blumenthal, Kenneth; Hicks, Leslie; Rouquié, David; Herman, Rod A.; Herouet-Guicheney, Corinne; Ladics, Gregory S.; McClain, Scott; Poulsen, Lars K.; Ward, Jason M.; Doerrer, Nancy; Privalle, Laura; Rascle, Jean-Baptiste; Teshima, Reiko (2015)
    In rice, several allergens have been identified such as the non-specific lipid transfer protein-1, the α-amylase/trypsin-inhibitors, the α-globulin, the 33 kDa glyoxalase I (Gly I), the 52–63 kDa globulin, and the ...
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    Inter-laboratory optimization of protein extraction, separation, and fluorescent detection of endogenous rice allergens 

    Satoh, Rie; Teshima, Reiko; Kitta, Kazumi; Lang, Gang-Hua; Schegg, Kathleen; Blumenthal, Kenneth; Hicks, Leslie; Labory-Carcenac, Bénédicte; Rouquie, David; Herman, Rod A.; Herouet-Guicheney, Corinne; Ladics, Gregory S.; McClain, Scott; Poulsen, Lars K.; Privalle, Laura; Ward, Jason M.; Doerrer, Nancy; Rascle, Jean-Baptiste (2016)
    In rice, several allergens have been identified such as the non-specific lipid transfer protein-1, the -amylase/trypsin-inhibitors, the -globulin, the 33kDa glyoxalase I (Gly I), the 52-63kDa globulin, and the granule-bound ...
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    Large-scale mRNA expression profiling in the common ice plant, Mesembryanthemum crystallinum, performing C3 photosynthesis and Crassulacean acid metabolism (CAM). 

    Cushman, John C.; Tillett, Richard L.; Wood, Joshua A.; Branco, Joshua M.; Schlauch, Karen A. (3/3/2008)
    The common ice plant (Mesembryanthemum crystallinum L.) has emerged as a useful model for molecular genetic studies of Crassulacean acid metabolism (CAM) because CAM can be induced in this species by water deficit or ...