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Now showing items 35-54 of 110

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    Effect of curcumin on amyloid-like aggregates generated from methionine-oxidized apolipoprotein A-I 

    Krishnamoorthy, Aparna; Tavoosi, Narjes; Chan, Gary K. L.; Liu, Jianfang; Ren, Gang; Cavigiolio, Giorgio; Ryan, Robert O. (2018)
    Curcumin is a polyphenolic phytonutrient that has antineurodegenerative properties. In this study, we investigated the anti-amyloidogenic properties of curcumin. Following incubation with curcumin, intrinsic tryptophan ...
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    The Emerging Role of Protein Phosphorylation as a Critical Regulatory Mechanism Controlling Cellulose Biosynthesis 

    Jones, Danielle M.; Murray, Christian M.; Ketelaar, KassaDee J.; Thomas, Joseph J.; Villalobos, Jose A.; Wallace, Ian S. (Frontiers in Plant Science, 2016)
    Plant cell walls are extracellular matrices that surround plant cells and critically influence basic cellular processes, such as cell division and expansion. Cellulose is a major constituent of plant cell walls, and this ...
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    Engineering crassulacean acid metabolism to improve water-use efficiency. 

    Borland, Anne M.; Hartwell, James; Weston, David J.; Schlauch, Karen A.; Tschaplinski, Timothy J.; Tuskan, Gerald A.; Yang, Xiaohan; Cushman, John C. (5/1/2014)
    Climatic extremes threaten agricultural sustainability worldwide. One approach to increase plant water-use efficiency is to introduce crassulacean acid metabolism (CAM) into C3 crops. Such a task requires comprehensive ...
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    EphB2 isolates a human marrow stromal cell subpopulation with enhanced ability to contribute to the resident intestinal cellular pool. 

    Colletti, Evan J.; El Shabrawy, Deena; Soland, Melisa; Yamagami, Takashi; Mokhtari, Saloomeh; Osborne, Craig D.; Schlauch, Karen A.; Zanjani, Esmail D.; Porada, Christopher D.; Almeida-Porada, Graça (6/1/2013)
    To identify human bone marrow stromal cell(BMSC) subsets with enhanced ability to engraft/contribute to the resident intestinal cellular pool, we transplanted clonally derived BMSCs into fetalsheep. Analysis at 75 d ...
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    ERCP and laparoscopic cholecystectomy in a combined (one-step) procedure: a random comparison to the standard (two-step) procedure. 

    Jones, M.; Johnson, Matthew; Samourjian, E.; Schlauch, Karen A.; Ozobia, N. (6/1/2013)
    Background—Current treatment of complicated calculous biliary disease typically involves a two-step procedure consisting of preoperative endoscopic retrograde cholangiopancreatography (ERCP) followed by laparoscopic ...
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    Evolution of l‐DOPA 4,5‐dioxygenase activity allows for recurrent specialisation to betalain pigmentation in Caryophyllales 

    Sheehan, Hester; Feng, Tao; Walker, Nathanael H.; Lopez, Samuel N.; Pucker, Boas; Guo, Ruijun; Yim, Won C.; Badgami, Roshani; Timoneda, Alfonso; Zhao, Lijun (2019)
    The evolution of L-DOPA 4, 5-dioxygenase activity, encoded by the gene DODA, was a keystep in the origin of betalain biosynthesis in Caryophyllales. We previously proposed that L-DOPA 4,5-dioxygenase activity evolved via ...
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    Evolution of Plant P-Type ATPases 

    Pedersen, Christian N. S.; Axelsen, Kristian B.; Harper, Jeffrey F.; Palmgren, Michael G. (2012)
    Five organisms having completely sequenced genomes and belonging to all major branches of green plants (Viridiplantae) were analyzed with respect to their content of P-type ATPases encoding genes. These were the chlorophytes ...
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    Five omic technologies are concordant in differentiating the biochemical characteristics of the berries of five grapevine (Vitis vinifera L.) cultivars 

    Ghan, Ryan M.; Van Sluyter, Steven C.; Hochberg, Uri; Degu, Asfaw; Hopper, Daniel W.; Tillet, Richard L.; Schlauch, Karen A.; Haynes, Paul A.; Fait, Aaron; Cramer, Grant R. (2015)
    Grape cultivars and wines are distinguishable by their color, flavor and aroma profiles. Omic analyses (transcripts, proteins and metabolites) are powerful tools for assessing biochemical differences in biological systems. ...
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    Frax prediction without BMD for assessment of osteoporotic fracture risk. 

    Gadam, Ramesh; Schlauch, Karen A.; Izuora, Kenneth (10/1/2013)
    To compare Fracture Risk Assessment Tool (FRAX) calculations with and without bone mineral density (BMD) in predicting the 10-year probability of hip and major osteoporotic fractures (MOF).
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    Functional genomics of mountain pine beetle (Dendroctonus ponderosae) midguts and fat bodies. 

    Aw, Tidiane; Schlauch, Karen A.; Keeling, Christopher I.; Young, Sharon L.; Bearfield, Jeremy C.; Blomquist, Gary J.; Tittiger, Claus (3/30/2010)
    Background: The mountain pine beetle (Dendroctonus ponderosae) is a significant coniferous forest pest in western North America. It relies on aggregation pheromones to colonize hosts. Its three major pheromone components, ...
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    Gene expression of the liver in response to chronic hypoxia. 

    Baze, Monica M.; Schlauch, Karen A.; Hayes, Jack P. (5/1/2010)
    Hypoxia is an important ecological, evolutionary, and biomedicalstressor. While physiological acclimatization of mammals to hypoxia is wellstudied, the variation in gene expression that underlies acclimatization is not ...
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    Genome-wide association analysis identifies genetic variations in subjects with myalgic encephalomyelitis/chronic fatigue syndrome 

    Schlauch, K. A.; Khaiboullina, Svetlana F.; De Meirleir, Kenny L.; Rawat, Shanti; Petereit, Julia; Rizvanov, A. A.; Blatt, N.; Mijatovic, Tatjana; Kulick, Doina; Palm, Kathleen M.; Lombardi, Vincent C. (2016)
    Myalgic encephalomyelitis, also known as chronic fatigue syndrome or ME/CFS, is a multifactorial and debilitating disease that has an impact on over 4 million people in the United States alone. The pathogenesis of ME/CFS ...
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    Genomic insights into the Ixodes scapularis tick vector of Lyme disease 

    Gulia-Nuss, Monika; Nuss, Andrew B.; Meyer, Jason M.; Sonenshine, Daniel E.; Roe, R. Michael; Waterhouse, Robert M.; Sattelle, David B.; de la Fuente, Jose; Ribeiro, Jose M.; Megy, Karine; Thimmapuram, Jyothi; Miller, Jason R.; Walenz, Brian P.; Koren, Sergey; Hostetler, Jessica B.; Thiagarajan, Mathangi; Joardar, Vinita S.; Hannick, Linda I.; Bidwell, Shelby; Hammond, Martin P.; Young, Sarah; Zeng, Qiandong; Abrudan, Jenica L.; Almeida, Francisca C.; Ayllon, Nieves; Bhide, Ketaki; Bissinger, Brooke W.; Bonzon-Kulichenko, Elena; Buckingham, Steven D.; Caffrey, Daniel R.; Caimano, Melissa J.; Croset, Vincent; Driscoll, Timothy; Gilbert, Don; Gillespie, Joseph J.; Giraldo-Calderon, Gloria I.; Grabowski, Jeffrey M.; Jiang, David; Khalil, Sayed M. S.; Kim, Donghun; Kocan, Katherine M.; Koci, Juraj; Kuhn, Richard J.; Kurtti, Timothy J.; Lees, Kristin; Lang, Emma G.; Kennedy, Ryan C.; Kwon, Hyeogsun; Perera, Rushika; Qi, Yumin; Radolf, Justin D.; Sakamoto, Joyce M.; Sanchez-Gracia, Alejandro; Severo, Maiara S.; Silverman, Neal; Simo, Ladislav; Tojo, Marta; Tornador, Cristian; Van Zee, Janice P.; Vazquez, Jesus; Vieira, Filipe G.; Villar, Margarita; Wespiser, Adam R.; Yang, Yunlong; Zhu, Jiwei; Arensburger, Peter; Pietrantonio, Patricia V.; Barker, Stephen C.; Shao, Renfu; Zdobnov, Evgeny M.; Hauser, Frank; Grimmelikhuijzen, Cornelis J. P.; Park, Yoonseong; Rozas, Julio; Benton, Richard; Pedra, Joao H. F.; Nelson, David R.; Unger, Maria F.; Tubio, Jose M. C.; Tu, Zhijian; Robertson, Hugh M.; Shumway, Martin; Sutton, Granger; Wortman, Jennifer R.; Lawson, Daniel; Wikel, Stephen K.; Nene, Vishvanath M.; Fraser, Claire M.; Collins, Frank H.; Birren, Bruce; Nelson, Karen E.; Caler, Elisabet; Hill, Catherine A. (2016)
    Ticks transmit more pathogens to humans and animals than any other arthropod. We describe the 2.1 Gbp nuclear genome of the tick, Ixodes scapularis (Say), which vectors pathogens that cause Lyme disease, human granulocytic ...
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    Glut4 Is Sorted from a Rab10 GTPase-independent Constitutive Recycling Pathway into a Highly Insulinresponsive Rab10 GTPase-dependent Sequestration Pathway after Adipocyte Differentiation 

    Brewer, Paul D.; Habtemichael, Estifanos N.; Romenskaia, Irina; Mastick, Cynthia C.; Coster, Adelle C. F. (2016)
    The RabGAP AS160/TBC1D4 controls exocytosis of the insulin-sensitive glucose transporter Glut4 in adipocytes. Glut4 is internalized and recycled through a highly regulated secretory pathway in these cells. Glut4 also cycles ...
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    Gut-associated plasmacytoid dendritic cells display an immature phenotype and upregulated granzyme B in subjects with HIV/AIDS 

    Boichuk, Sergei V.; Khaiboullina, Svetlana F.; Ramazanov, Bulat R.; Khasanova, Gulshat R.; Ivanovskaya, Karina A.; Nizamutdinov, Evgeny Z.; Sharafutdinov, Marat R.; Martynova, Ekaterina V.; DeMeirleir, Kenny L.; Hulstaert, Jan; Anokhin, Vladimir A.; Rizvanov, Albert A.; Lombardi, Vincent C. (2015)
    Plasmacytoid dendritic cells (pDCs) in the periphery of subjects with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) decrease over time, and the fate of these cells has been the subject of ...
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    GWAS and PheWAS of red blood cell components in a Northern Nevadan cohort 

    Read, Robert W.; Schlauch, Karen A.; Elhanan, Gai; Metcalf, William J.; Slonim, Anthony D.; Aweti, Ramsey; Borkowski, Robert; Grzymski, Joseph J. (PLoS ONE, 2019)
    In this study, we perform a full genome-wide association study (GWAS) to identify statistically significantly associated single nucleotide polymorphisms (SNPs) with three red blood cell (RBC) components and follow it with ...
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    Hantavirus Infection Suppresses Thrombospondin-1 Expression in Cultured Endothelial Cells in a Strain-Specific Manner 

    Khaiboullina, Svetlana F.; Morzunov, Sergey P.; St Jeor, Stephen C.; Rizvanov, Albert A.; Lombardi, Vincent C. (2016)
    Hantavirus infection is associated with two frequently fatal diseases in humans: Hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS). The pathogenesis of hantavirus infection is complex and ...
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    High quality draft genome sequences of Mycoplasma agassizii strains PS6(T) and 723 isolated from Gopherus tortoises with upper respiratory tract disease 

    Alvarez-Ponce, David; Weitzman, Chava L.; Tillett, Richard L.; Sandmeier, Franziska C.; Tracy, C. Richard (2018)
    Mycoplasma agassizii is one of the known causative agents of upper respiratory tract disease (URTD) in Mojave desert tortoises (Gopherus agassizii) and in gopher tortoises (Gopherus polyphemus). We sequenced the genomes ...
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    Humoral Immunity Profiling of Subjects with Myalgic Encephalomyelitis Using a Random Peptide Microarray Differentiates Cases from Controls with High Specificity and Sensitivity 

    Singh, Sahajpreet; Stafford, Phillip; Schlauch, Karen A.; Tillett, Richard R.; Gollery, Martin; Johnston, Stephen A.; Khaiboullina, Svetlana F.; De Meirleir, Kenny L.; Rawat, Shanti; Mijatovic, Tatjana; Subramanian, Krishnamurthy; Palotas, Andras; Lombardi, Vincent C. (2018)
    Myalgic encephalomyelitis (ME) is a complex, heterogeneous illness of unknown etiology. The search for biomarkers that can delineate cases from controls is one of the most active areas of ME research however, little progress ...
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    Identification of genes encoding enzymes catalyzing the early steps of carrot polyacetylene biosynthesis 

    Busta, Lucas; Yim, Won C.; LaBrant, Evan W.; Wang, Peng; Grimes, Lindsey; Malyszka, Kiah; Cushman, John C.; Santos, Patricia; Kosma, Dylan K.; Cahoon, Edgar B. (2018)
    Polyacetylenic lipids accumulate in various Apiaceae species after pathogen attack, suggesting that these compounds are naturally occurring pesticides and potentially valuable resources for crop improvement. These compounds ...