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Browsing Electronic Theses and Dissertations by Subject "Macrocyclization"
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Synthesis and Structure-Activity Relationship Studies of Cyclotriaza Compounds as CD4 Down-Modulators and Anti-HIV Agents (2014)Cyclotriazadisulfonamide (CADA) inhibits human immunodeficiency virus (HIV) by down-modulating cell surface CD4 receptor expression. More specifically, CADA inhibits co-translational translocation of nascent human CD4 ...