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Now showing items 211-219 of 219
Functional Role of ClC-3 Chloride Channels in Myocardial Hypertrophy and Heart Failure
Background: In hypertrophied cardiac myocytes the volume-regulated chloride channels (VRCCs) are activated constitutively. But the functional role and molecular mechanism of the constitutively activated VRCCs in myocardial ...
Functional Characterization of Fatty Acyl-Reductase CG17560 in Drosophila Melanogaster
Over the past few decades, there has been growing interest in biofuel development to supplement current energy sources, with different approaches being explored. Use of enzymes from insects, such as fatty-acyl reductases ...
The Transcriptome Response of Chaetoceros socialis during Moderate Silica Limitation
Diatoms are ubiquitous microorganisms important in the global carbon cycle, because of their significant primary productivity. These phytoplankton require the nutrient silica to form their outer cell wall, however, surface ...
Role of COP9 signalosome subunit 3 (CSN3) phosphorylation in integrin-mediated cardiac hypertrophy
Integrins are involved in various aspects of cell regulation, signaling, and growth and have been shown to react to environmental stimuli such as mechanical stress in cardiac myocytes. These integrin-mediated reactions ...
Arabidopsis thaliana P4-type ATPases ALA4 and ALA5 are Necessary for Normal Cellular Elongation in Developing Vegetative Tissues and Rescue the Pollen Tube Deficiencies in Knockout ala6/7 Mutants
Members of the P4 subfamily of P-type ATPases (lipid flippases) have been shown to incorporate specific lipids into cellular membranes, as well as flip lipids from one leaflet to another to create an asymmetric distribution ...
The lipases of T cells and their function in cytotoxicity
Cytotoxic T lymphocytes (CTLs) eliminate virally infected cells and tumor cells through the use of cytotoxic proteins and death-inducing ligands. Through decades of research, scientists have identified and characterized ...
Characterization of the Putative A. thaliana Protein O-fucosyltransferase OFT1 which is Essential for Plant Reproduction
AbstractIn flowering plants, pollen tubes grow from the pollen grain in a polarized mannerin order to deliver two haploid non-motile sperm cells to the female gamete. Thefollowing fertilization event results in the formation ...
Testing the Role of Cyclic Nucleotides in Regulating Ion Channels Essential to Pollen Fertility
It is unknown if plant cyclic nucleotide gated channels (CNGCs) are activated by cyclic nucleotide monophosphates (cNMPs, e.g. cAMP or cGMP), or even if cNMPs are present at physiologically significant levels in plants. ...
Identifying a Growth Restoring Mutant in ala4/5 Dwarf Plants with PCR Diagnostics
Aminophospholipid ATPases (ALAs) are lipid flippases that are involved in the uptake and translocation of specific lipids across membrane bilayers. Research demonstrates that ALA4 and ALA5 are critical to proper vegetative ...