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Production and purification of recombinant human laminin-111 for pre-clinical testing in a murine model of laminin-α2 deficient congenital muscular dystrophy
Laminin α2-deficient congenital muscular dystrophy (LAMA2-CMD) is a fatal genetic neuromuscular disease that currently has no cure. Patients with LAMA2-CMD suffer from muscle wasting, respiratory issues, and neurological ...