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Investigating Glycosylation and Phosphorylcholine Post-Translational Modifications in the Free-Living Nematode, Caenorhabditis elegans
Caenorhabditis elegans is a classic genetic model, but biochemistry in the worm has not kept pace. For many reasons, some of which are described in Chapter 1, C. elegans is an ideal model to interrogate post-translatio ...
Development of a chemical biology approach for glycoprotein discovery in Caenorhabditis elegans reveals glycosylated isoforms of multiple proteins with mitochondrial function
Proper glycosylation is critical for cellular physiology and organism health. But understanding the cellular pathways that produce glycoproteins and the functional roles these glycoproteins play within the cell depends ...
Mechanisms of Feeding State Dependent Chemoreceptor Gene Expression in C. elegans
Animals dramatically modify their chemosensory behaviors when starved, which could allow them to alter and optimize their food-search strategies. Dynamic changes in the gene expression of chemoreceptors may be a general ...