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Antibody-based diagnostics and therapeutics for Zaire ebolavirus and Burkholderia pseudomallei
Zaire ebolavirus (EBOV) and Burkholderia pseudomallei are the causative agents of Ebola virus disease (EVD) and melioidosis, respectively. Early diagnosis is critical for halting the spread of the disease or providing ...
Detection and in vivo fate of surface-expressed bacterial polysaccharides
The potential bioterrorism agents, Francisella tularensis and Burkholderia pseudomallei, are the etiologic agents of two life-threatening diseases, termed tularemia and melioidosis, respectively. An early diagnosis and a ...
Identification of Circulating Burkholderia pseudomallei Antigens and Development of Chimeric Antibodies
Burkholderia pseudomallei is the causative agent of melioidosis, an emerging tropical disease. Thousands contract this disease every year, mainly in Southeast Asia and northern Australia. Disease manifestations range from ...
Antibody interactions with the capsular polysaccharide of Burkholderia pseudomallei
Burkholderia pseudomallei is an important human pathogen that causes melioidosis. Infection is highly lethal and notoriously difficult to diagnose and treat. As such, it has tremendous bioterror potential and has been ...