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MicroRNA Post-transcriptional Regulation of the NLRP3 Inflammasome in Immunopathologies
Inflammation has a crucial role in protection against various pathogens. The inflammasome is an intracellular multiprotein signaling complex that is linked to pathogen sensing and initiation of the inflammatory response ...
An ecoimmunological approach to disease in tortoises reveals the importance of lymphocytes
We quantified the severity of upper respiratory tract disease (URTD) and immunological metrics (differential white blood cell counts and bacteria-killing ability of blood plasma) in relation to climatic variables in 20 ...
Utilization of Imaging to Identify a Benign Condition Mimicking Acute Appendicitis in a Child
(Journal of Investigative Medicine High Impact Case Reports, 2018)
One of the most concerning causes of abdominal pain affecting children is acute appendicitis. However, there are benign conditions that can closely mimic appendicitis in children. In this article, we present a case of a ...
Biomedical approach in autism spectrum disorders-the importance of assessing inflammation
(AIMS Molecular Science, 2018)
Autism spectrum disorders (ASD) are severe heterogeneous neurodevelopmental disorders characterized by dysfunctions in social interaction and communication skills, repetitive and stereotypic verbal and nonverbal behaviors. ...
MicroRNA expression in human airway smooth muscle cells: role of miR-25 in regulation of airway smooth muscle phenotype.
Defining mechanisms by which differentiated, contractile smooth muscle cells become proliferative and secretory in response to mechanical and environmental stress is crucial for determining the contribution of airway smooth ...
Transcriptome Profiling Reveals Pro-Inflammatory Cytokines and Matrix Metalloproteinase Activation in Zika Virus Infected Human Umbilical Vein Endothelial Cells
The deformities in the newborns infected with Zika virus (ZIKV) present a new potential public health threat to the worldwide community. Although ZIKV infection is mainly asymptomatic in healthy adults, infection during ...