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Insulin-like growth factors and their potential role in cardiac epigenetics
Cardiovascular disease (CVD) constitutes a major public health threat worldwide, accounting for 17.3 million deaths annually. Heart disease and stroke account for the majority of healthcare costs in the developed world. ...
Inhibition of A beta(42) oligomerization in yeast by a PICALM ortholog and certain FDA approved drugs
The formation of small A beta 42 oligomers has been implicated as a toxic species in Alzheimer disease (AD). In strong support of this hypothesis we found that overexpression of Yap1802, the yeast ortholog of the human AD ...