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GWAS in childhood acute lymphoblastic leukemia reveals novel genetic associations at chromosomes 17q12 and 8q24.21
(Nature Communications, 2018)
Childhood acute lymphoblastic leukemia (ALL) (age 0-14 years) is 20% more common in Latino Americans than non-Latino whites. We conduct a genome-wide association study in a large sample of 3263 Californian children with ...
A germ-line deletion of APOBEC3B does not contribute to subtype-specific childhood acute lymphoblastic leukemia etiology
Approximately 4/100,000 children are diagnosed with acute lymphoblastic leukemia (ALL) in the United States annually. Early life exposures related to immune priming (i.e. vaginal birth, daycare attendance, and high birth ...