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DUSP5 functions as a feedback regulator of TNF alpha-induced ERK1/2 dephosphorylation and inflammatory gene expression in adipocytes
(Scientific Reports, 2017)
Adipose tissue inflammation is a central pathological element that regulates obesity-mediated insulin resistance and type II diabetes. Evidence demonstrates that extracellular signal-regulated kinase (ERK 1/2) activation ...
A Mathematical Model for Suppression Subtractive Hybridization
Suppression subtractive hybridization (SSH) is frequently used to unearth differentially expressed genes on a whole-genome scale. Its versatility is based on combining cDNA library subtraction and normalization, which ...
Insulin-Like Peptide Signaling in Mosquitoes: The Road Behind and the Road Ahead
Insulin signaling is a conserved pathway in all metazoans. This pathway contributed toward primordial metazoans responding to a greater diversity of environmental signals by modulating nutritional storage, reproduction, ...
Natural product inhibitors of acetyl-lysine erasers in the prevention and treatment of heart failure
(Functional Foods in Health and Disease, 2017)
Heart failure (HF) is a major public health concern, with five-year mortality rates following first admission for HF being approximately 50%, thereby stressing the need for novel therapeutic approaches. Histone deacetylases ...
Dynamics of Insulin Signaling in the Black-Legged Tick, Ixodes scapularis
Insulin-like peptides (ILPs) have been identified in several invertebrates, particularly insects, and work on these ILPs has revealed many roles including regulation of energy homeostasis, growth, development, and lifespan ...
Harvest management based on leaf stage of a tetraploid vs. a diploid cultivar of annual ryegrass
(Grass and Forage Science, 2017)
Leaf stage-dependent defoliation is linked to the plant's physiological status and may be a more suitable criterion than time-based intervals for harvesting forage grasses, but no reports of research with annual ryegrass ...
Food Bioactive HDAC Inhibitors in the Epigenetic Regulation of Heart Failure
Approximately 5.7 million U.S. adults have been diagnosed with heart failure (HF). More concerning is that one in nine U.S. deaths included HF as a contributing cause. Current HF drugs (e.g., -blockers, ACEi) target ...
Extracting Plant Phenology Metrics in a Great Basin Watershed: Methods and Considerations for Quantifying Phenophases in a Cold Desert
Plant phenology is recognized as important for ecological dynamics. There has been a recent advent of phenology and camera networks worldwide. The established PhenoCam Network has sites in the United States, including the ...
Growth, Root Formation, and Nutrient Value of Triticale Plants Fertilized with Biosolids
Biosolids are utilized as nutrient rich fertilizer. Little material is available on benefits to forage crops resulting from fertilization with biosolids. This paper aimed to compare the effects of fertilization with biosolids ...
Does partial replacement of corn with glycerin in beef cattle diets affect in vitro ruminal fermentation, gas production kinetic, and enteric greenhouse gas emissions?
Five in vitro experiments were conducted with the following objectives: 1) To evaluate the ruminal fermentation of three different single ingredients: corn, glycerin, and starch (Exp. 1 and 2)