Now showing items 1-5 of 5
Insulin receptor knockdown blocks filarial parasite development and alters egg production in the southern house mosquito, Culex quinquefasciatus
Lymphatic filariasis, commonly known as elephantiasis, is a painful and profoundly disfiguring disease. Wuchreria bancrofti (Wb) is responsible for >90% of infections and the remainder are caused by Brugia spp. Mosquitoes ...
Genomic insights into the Ixodes scapularis tick vector of Lyme disease
Ticks transmit more pathogens to humans and animals than any other arthropod. We describe the 2.1 Gbp nuclear genome of the tick, Ixodes scapularis (Say), which vectors pathogens that cause Lyme disease, human granulocytic ...
Insulin-Like Peptide Signaling in Mosquitoes: The Road Behind and the Road Ahead
Insulin signaling is a conserved pathway in all metazoans. This pathway contributed toward primordial metazoans responding to a greater diversity of environmental signals by modulating nutritional storage, reproduction, ...
Nutritional Quality during Development Alters Insulin-Like Peptides' Expression and Physiology of the Adult Yellow Fever Mosquito, Aedes aegypti
Mosquitoes have distinct developmental and adult life history, and the vectorial capacity of females has been shown to be affected by the larval nutritional environment. However, little is known about the effect of ...
Dynamics of Insulin Signaling in the Black-Legged Tick, Ixodes scapularis
Insulin-like peptides (ILPs) have been identified in several invertebrates, particularly insects, and work on these ILPs has revealed many roles including regulation of energy homeostasis, growth, development, and lifespan ...