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Zeptonewton force sensing with nanospheres in an optical lattice
(2016)Optically trapped nanospheres in high vacuum experience little friction and hence are promising for ultrasensitive force detection. Here we demonstrate measurement times exceeding 10(5) s and zeptonewton force sensitivity ... -
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Zika Virus: Medical Countermeasure Development Challenges
(2016)Introduction Reports of high rates of primary microcephaly and Guillain-Barre syndrome associated with Zika virus infection in French Polynesia and Brazil have raised concerns that the virus circulating in these regions ... -
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ZIKV infection regulates inflammasomes pathway for replication in monocytes
(2017)ZIKV causes microcephaly by crossing the placental barrier, however, the mechanism of trans-placental dissemination of ZIKV remains unknown. Here, we sought to determine whether monocytes, which can cross tissue barriers, ... -
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ZnS nanoparticles sensitize luminescence of capping-ligand bound lanthanide ions
(2017)2,6-Bis(diethylamide)-4-oxo(3-thiopropane)pyridine (BDP) and 2,6-bis(methyl ester)-4-oxo(3-thiopropane)pyridine (BMP) were synthesized. These compounds chelated LnIII ions and sensitized their emission. The 3:1 complexes ... -
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α7-integrin enhancing compounds regulate α7β1-integrin and laminin-α2 expression in airway smooth muscle cells via miRNA-mediated gene silencing mechanisms
(2016)Asthma is characterized by airway inflammation, mucus production, and airway smooth muscle hyperreactivity that result in difficulty breathing. There has been an increasing need to develop new treatments for asthma that ...